Anafilaxia: estado del arte

Julian Londoño, Maria Mercedes Raigosa, Maria Vásquez, Jorge Sánchez

Resumen


La anafilaxia se define como una reacción de hipersensibilidad, sistémica, de instauración rápida y potencialmente fatal, con manifestaciones clínicas y severidad variable, que resulta de la liberación súbita de mediadores de mastocitos y basófilos. El diagnóstico de esta entidad es fundamentalmente clínico, basándose en los patrones de manifestación y la exposición a un posible detonante. Actualmente varios estudios indican deficiencias en la identificación y manejo de esta enfermedad, lo que genera un riesgo elevado de mortalidad.

En esta revisión presentamos puntos prácticos del manejo e identificamos las principales consideraciones a tener en cuenta en el primer nivel de atención.


Palabras clave


Adrenalina; Alimentos; Alérgeno; Anafilaxia; Atopia; Epinefrina; Medicamentos

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Referencias


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