Sarcoidosis: muchas caras, una enfermedad. Revisión narrativa de la literatura

Andrés Chavarriaga-Restrepo, Juan Esteban López-Amaya, Miguel Antonio Mesa-Navas, Carlos Jaime Velásquez-Franco

Resumen


La sarcoidosis es una enfermedad granulomatosa sistémica de etiología desconocida. Esta puede afectar a pacientes de todas las latitudes y edades, siendo más frecuente entre la tercera y cuarta década de la vida con un segundo pico alrededor de los 50 años en las poblaciones escandinava y japonesa. Es más frecuente en mujeres y grave en la población afrodescendiente.

Los antígenos que inician esta respuesta granulomatosa son desconocidos, pero se presume que son aerotransportados por la alta frecuencia de compromiso pulmonar en esta enfermedad. Su presentación clínica abarca una amplia gama de manifestaciones, desde formas agudas y limitadas hasta el compromiso crónico con daño orgánico progresivo y muerte. Su diagnóstico se basa en la existencia de los granulomas no caseificantes en los tejidos, con la exclusión de otras enfermedades, entre ellas infección por micobacterias.

 


Palabras clave


Linfadenopatía; Pulmón; Sarcoidosis

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Referencias


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DOI: https://doi.org/10.17533/udea.iatreia.11 Resumen : 255 PDF : 235 PDF (English) : 10

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